RT Journal Article
SR Electronic
A1 Cunningham, Muriel
T1 Single-Center Study Finds Bivalirudin Associated with Increased Ischemic Risk in Primary PCI for STEMI (HEAT PPCI)
JF MD Conference Express
YR 2014
FD SAGE Publications
VO 14
IS 4
SP 26
OP 27
DO 10.1177/155989771404016
UL http://mdc.sagepub.com/content/14/4/26.abstract
AB This article presents results from the How Effective Are Antithrombotic Therapies in Primary Percutaneous Coronary Intervention trial [HEAT PPCI; NCT01519518]. All patients with ST-segment elevation myocardial infarction presenting at a single United Kingdom center were randomized to open-label treatment with heparin (70 units/kg body weight preprocedure) or bivalirudin (bolus of 0.75 mg/kg followed by 1.75 mg/kg/hour infusion during the procedure) on top of preprocedure dual antiplatelet therapy.