RT Journal Article SR Electronic A1 Parry, Nicola T1 First-Line Antidepressants Produce Similar Responses in Major Depressive Disorder JF MD Conference Express YR 2014 FD SAGE Publications VO 14 IS 8 SP 16 OP 17 DO 10.1177/155989771408008 UL http://mdc.sagepub.com/content/14/8/16.2.abstract AB This article presents results from the first half of the randomized controlled International Study to Predict Optimized Treatment in Depression [iSPOT-D; NCT00693849]. The study demonstrated that, for patients with major depressive disorder, escitalopram, sertraline, and venlafaxine extended release produced similar treatment response rates, with mild and similar side effects.