PT - JOURNAL ARTICLE AU - Buckley, Rita ED - Perol, Maurice TI - Ramucirumab Improves Survival in Stage IV NSCLC DP - 2014 Aug 01 TA - MD Conference Express PG - 14--14 VI - 14 IP - 14 4099 - http://mdc.sagepub.com/content/14/14/14.short 4100 - http://mdc.sagepub.com/content/14/14/14.full AB - Ramucirumab (IMC-1121B) is a human immunoglobulin G1 monoclonal antibody that targets the extracellular domain of vascular endothelial growth factor receptor 2. A Study of Chemotherapy and Ramucirumab versus Chemotherapy Alone in Second Line Non—Small Cell Lung Cancer Participants Who Received Prior First Line Platinum Based Chemotherapy [REVEL; NCT01168973; Garon EB et al. Lancet 2014] showed that ramucirumab combined with docetaxel extended survival in patients with advanced non—small cell lung cancer (NSCLC) compared with placebo plus docetaxel.