PT - JOURNAL ARTICLE AU - Parry, Nicola ED - Criner, Gerard J. TI - Lowering the Influence of Exacerbations in COPD DP - 2014 Sep 01 TA - MD Conference Express PG - 30--33 VI - 14 IP - 11 4099 - http://mdc.sagepub.com/content/14/11/30.short 4100 - http://mdc.sagepub.com/content/14/11/30.full AB - This article discusses the significance of exacerbations and rehospitalizations in chronic obstructive pulmonary disease (COPD) in contributing to the high mortality rate associated with the disease. Recent data were also highlighted, showing that human rhinovirus (HRV) infection is common in frequent exacerbators, and how secondary bacterial infection may represent a mechanism for exacerbation recurrence and therefore a potential target for novel therapies.