RT Journal Article
SR Electronic
A1 Mosley, Mary
T1 COPD Exacerbations Not Prevented with Simvastatin in STATSCOPE Study
JF MD Conference Express
YR 2014
FD SAGE Publications
VO 14
IS 11
SP 13
OP 14
DO 10.1177/155989771411007
UL http://mdc.sagepub.com/content/14/11/13.2.abstract
AB Simvastatin in addition to usual care did not reduce the rate of or time to exacerbations in patients with moderate to severe chronic obstructive pulmonary disease (COPD) in the Simvastatin Therapy for Moderate and Severe COPD study [STATCOPE; NCT01061671; Criner GJ et al. N Engl J Med 2014]. This multicenter study conducted in the United States and Canada and sponsored by respective federal agencies sought to validate benefits seen with statins, perhaps related to their anti-inflammatory effects, in retrospective studies of COPD.