RT Journal Article SR Electronic A1 Shuman, Jill T1 RFA or Antiarrythmic Drug Therapy for Symptomatic AF? JF MD Conference Express YR 2014 FD SAGE Publications VO 14 IS 21 SP 22 OP 23 DO 10.1177/155989771421012 UL http://mdc.sagepub.com/content/14/21/22.2.abstract AB Radiofrequency ablation (RFA) has emerged as an effective therapy for patients with paroxysmal atrial fibrillation (PAF) [Stabile G et al. Eur Heart J 2006], and at least 1 international consensus document concludes that ablation is an acceptable first option for patients with symptomatic PAF [Caulkins H et al. Europace 2012]. However, limited data are available comparing this technology with antiarrhythmic drug therapy as first-line treatment for patients with PAF. This article discusses 24-month outcomes from the Medical Antiarrhythmic Treatment or Radiofrequency Ablation in Paroxysmal Atrial Fibrillation trial [MANTRA-PAF; Cosedis Nielsen J et al. N Engl J Med 2012].