PT  - JOURNAL ARTICLE
AU  - Rizzo, Toni
ED  - Halperin, Jonathan L.
TI  - IMPACT Study: Rhythm-Guided Anticoagulation Therapy Did Not Improve Outcomes
DP  - 2014 Sep 01
TA  - MD Conference Express
PG  - 14--15
VI  - 14
IP  - 21
4099  - http://mdc.sagepub.com/content/14/21/14.short
4100  - http://mdc.sagepub.com/content/14/21/14.full
AB  - Thromboembolism (TE) risk appears to be related to the burden of device-detected atrial tachyarrhythmias (AT) [Glotzer TV et al. Circ Arrhythm Electrophysiol 2009]. The investigators of the single-blinded Combined Use of BIOTRONIK Home Monitoring and Predefined Anticoagulation to Reduce Stroke Risk Trial [IMPACT; NCT00559988] hypothesized that a home monitoring—guided oral anticoagulation strategy, including initiation early after AT detection and withdrawal after a prespecified window without AT, might reduce TE and hemorrhage in patients with an implantable cardioverter-defibrillator or cardiac resynchronization therapy defibrillator device.