PT - JOURNAL ARTICLE AU - Lederman, Lynne ED - D'Hoore, Andre TI - More Research is Needed to Determine Optimal Therapies for Rectal Cancer DP - 2014 Nov 01 TA - MD Conference Express PG - 29--30 VI - 14 IP - 22 4099 - http://mdc.sagepub.com/content/14/22/29.short 4100 - http://mdc.sagepub.com/content/14/22/29.full AB - Rectal cancer is treated with surgery, radiation therapy (RT), and neoadjuvant and adjuvant chemotherapy (CT); yet, the best way to sequence and combine these modalities is not yet known. This article discusses organ-sparing surgery in rectal cancer, the feasibility of intensifying preoperative RT, as well as preoperative therapy.