RT Journal Article
SR Electronic
A1 Mosley, Mary
T1 COPPS-2: Colchicine Reduced PPS in Cardiac Surgery Patients
JF MD Conference Express
YR 2014
FD SAGE Publications
VO 14
IS 27
SP 15
OP 16
DO 10.1177/155989771427009
UL http://mdc.sagepub.com/content/14/27/15.2.abstract
AB Colchicine (COL) administered perioperatively in patients undergoing cardiac surgery reduced the incidence of the primary end point of postpericardiotomy syndrome (PPS) compared with placebo. Secondary end points of postoperative atrial fibrillation (POAF) and postoperative pleural and pericardial effusions were not significantly reduced in an investigator-initiated, double-blind, randomized clinical trial conducted at 11 centers in Italy. This article presents the results of the Colchicine for Prevention of the Post-pericardiotomy Syndrome and Post-operative Atrial Fibrillation trial [COPPS-2; Imazio M et al. JAMA. 2014].