RT Journal Article
SR Electronic
A1 Buckley, Rita
T1 Phaxan Proves Superior to Propofol in First-in-Human Study
JF MD Conference Express
YR 2014
FD SAGE Publications
VO 14
IS 40
SP 14
OP 14
DO 10.1177/155989771440008
UL http://mdc.sagepub.com/content/14/40/14.abstract
AB The Phase 1c Trial Comparing the Anaesthetic Pro-perties of Phaxan and Propofol [ACTRN 126000343909] was a double-blind study based on a Bayesian algorithm to determine dose equivalents for effects on the bispectral index. Its aims were to find the dose of Phaxan that caused anesthesia and to compare it with propofol for speed of onset and recovery, cardiovascular and respiratory effects, and other measures of safety and efficacy.