RT Journal Article SR Electronic A1 Kuznar, Wayne T1 Treatment Paradigms for MPNs Continue to Evolve JF MD Conference Express YR 2014 FD SAGE Publications VO 14 IS 55 SP 28 OP 30 DO 10.1177/1559897714568643 UL http://mdc.sagepub.com/content/14/55/28.abstract AB Ten years after the identification of the JAK2V617F mutation in most patients with myeloproliferative neoplasms, the understanding of the pathophysiology and genomic landscape of MPNs has evolved. The enhanced understanding and recognition of the impact of symptomatic burden on risk have led to targeted therapies and new treatment paradigms.