PT  - JOURNAL ARTICLE
AU  - Hoyle, Brian
ED  - Thompson, Philip A.
TI  - CKT Implicated in Worse Outcomes With Ibrutinib Therapy of CLL
DP  - 2014  01
TA  - MD Conference Express
PG  - 16--17
VI  - 14
IP  - 55
4099  - http://mdc.sagepub.com/content/14/55/16.2.short
4100  - http://mdc.sagepub.com/content/14/55/16.2.full
AB  - The outcome of patients with chronic lymphocytic leukemia treated with ibrutinib-based regimens indicates that complex metaphase karyotype is a more important predictor of outcome than del(17p). Lack of complex karyotype is associated with less-frequent disease progression. Patients with complex karyotype may be an ideal group in which to study novel treatments.