RT Journal Article
SR Electronic
A1 Vinall, Maria
T1 Clonal Mapping of Hematopoiesis In Vivo Provides Direction for New Clinical Protocols
JF MD Conference Express
YR 2014
FD SAGE Publications
VO 14
IS 55
SP 6
OP 6
DO 10.1177/1559897714568628
UL http://mdc.sagepub.com/content/14/55/6.abstract
AB Retroviral vectors are widely used in gene therapy for a variety of monogenic disorders, although several studies have noted an increase in adverse events. The ability to analyze vector integration sites is important for safety monitoring. This study provides information on molecular tracking of individual hematopoietic clones in humans.