PT - JOURNAL ARTICLE AU - Vinall, Maria ED - Grozovsky, Renata TI - JAK2-STAT3 Signaling Implicated in the Regulation of Hepatic TPO Production DP - 2014 01 TA - MD Conference Express PG - 4--5 VI - 14 IP - 55 4099 - http://mdc.sagepub.com/content/14/55/4.short 4100 - http://mdc.sagepub.com/content/14/55/4.full AB - New research findings can now explain the complete pathway for the regulation of thrombopoietin production, which regulates the production of platelets. Platelets lacking sialic acid due to aging are removed by the Ashwell-Morell receptor. The signaling pathways Janus kinase 2 and signal transducer and activator of transcription 3 then stimulates the production of thrombopoietin within the hepatocyte nucleus.