Summary

Results of the preplanned interim analysis of the Adjuvant Avastin Trial in High-Risk Melanoma trial [AVAST-M; ISRCTN81261306; EudraCT 2006-005505-64; Corrie P et al. J Clin Oncol 2013 (suppl; abstr LBA9000)] of melanoma patients at high risk of recurrence has shown that adjuvant bevacizumab (BEV) monotherapy is well tolerated and improved disease-free interval. Longer follow-up is required to determine an impact on the primary endpoint of 5-year overall survival.