RT Journal Article
SR Electronic
A1 Rizzo, Toni
T1 Abatacept and Adalimumab Equally Effective for Rheumatoid Arthritis
JF MD Conference Express
YR 2013
FD SAGE Publications
VO 13
IS 8
SP 6
OP 7
DO 10.1177/155989771308002
UL http://mdc.sagepub.com/content/13/8/6.abstract
AB To date, few direct comparisons of biologic agents for the treatment of rheumatoid arthritis (RA) have been conducted, resulting in a lack of evidence-based guidance for selection of biologic therapy. The Abatacept Versus Adalimumab Comparison in Biologic-Naïve RA Subjects With Background Methotrexate trial [AMPLE; NCT00929864] was the first powered head-to-head study comparing two biologic disease-modifying antirheumatic drugs, abatacept and adalimumab, with the standard of care, methotrexate. This article discusses Phase 3b of the AMPLE trial.