RT Journal Article
SR Electronic
A1 Hand, Larry
T1 Physiological Diagnostic Algorithm Tracks Ventilation and Workload in Patients with Heart Failure
JF MD Conference Express
YR 2013
FD SAGE Publications
VO 13
IS 12
SP 15
OP 15
DO 10.1177/155989771312005
UL http://mdc.sagepub.com/content/13/12/15.1.abstract
AB A physiological diagnostic (PhD) algorithm in a cardiac resynchronization device called Paradym (Paradym CRT+PhD) has a low sensitivity of 34% and a false-positive rate of 2.4 per patient year. This article reports on the results the trial Evaluation of a Diagnostic Feature in a Cardiac Resynchronization Therapy Device [CLEPSYDRA; NCT00957541]. A subanalysis of the study provided the basis for development of an alternative device-derived risk stratifier of heart failure (HF) events, identifying patients likely to develop HF decompensation in the following month with a Hazard Ratio of 4.4 [Gold M et al. EuroPace 2013 (abstr P1511)].