PT  - JOURNAL ARTICLE
AU  - Hand, Larry
ED  - Leyva, Francisco
TI  - Physiological Diagnostic Algorithm Tracks Ventilation and Workload in Patients with Heart Failure
DP  - 2013 Sep 01
TA  - MD Conference Express
PG  - 15--15
VI  - 13
IP  - 12
4099  - http://mdc.sagepub.com/content/13/12/15.1.short
4100  - http://mdc.sagepub.com/content/13/12/15.1.full
AB  - A physiological diagnostic (PhD) algorithm in a cardiac resynchronization device called Paradym (Paradym CRT+PhD) has a low sensitivity of 34% and a false-positive rate of 2.4 per patient year. This article reports on the results the trial Evaluation of a Diagnostic Feature in a Cardiac Resynchronization Therapy Device [CLEPSYDRA; NCT00957541]. A subanalysis of the study provided the basis for development of an alternative device-derived risk stratifier of heart failure (HF) events, identifying patients likely to develop HF decompensation in the following month with a Hazard Ratio of 4.4 [Gold M et al. EuroPace 2013 (abstr P1511)].