RT Journal Article
SR Electronic
A1 Vinall, Maria
T1 Changing Paradigms regarding New Antiplatelet Therapy
JF MD Conference Express
YR 2013
FD SAGE Publications
VO 13
IS 13
SP 24
OP 25
DO 10.1177/155989771313012
UL http://mdc.sagepub.com/content/13/13/24.abstract
AB Since early studies showing that aspirin reduces the incidence of death and myocardial infarction in patients with unstable angina [Wallentin LC. J Am Coll Cardiol 1991], there has been a search for more effective antithrombotic drugs. The ideal antiplatelet agent should minimize the risk of bleeding risk while maintaining ischemic protection. This article reviews several of the clinical trials that have lead to the paradigm shift in antiplatelet therapy.