PT  - JOURNAL ARTICLE
AU  - Rizzo, Toni
ED  - Smith, Ulf
TI  - Hypertrophic Obesity is Associated with Inflammation and Insulin Resistance
DP  - 2013 Dec 01
TA  - MD Conference Express
PG  - 10--11
VI  - 13
IP  - 16
4099  - http://mdc.sagepub.com/content/13/16/10.2.short
4100  - http://mdc.sagepub.com/content/13/16/10.2.full
AB  - Obesity causes changes in adipose tissue, the liver, and skeletal muscle that lead to systemic inflammation and insulin resistance. Obese individuals who have the ability to recruit new adipocytes develop adipocyte hyperplasia, whereas others have adipocyte hypertrophy due to impaired adipogenesis. The ability to recruit new adipocytes protects against ectopic fat accumulation in the abdomen, skeletal muscle, and liver.