Vaccine Efficacy in the Total Vaccine Cohort-Naïve.
CIN2+=cervical intraepithelial neoplasia grade 2 or greater; CIN3+=CIN grade 3 or greater; TVC=total vaccine cohort.Reprinted from Lehtinen M et al. Overall efficacy of HPV-16/18 AS04-adjuvanted vaccine against grade 3 or greater cervical intraepithelial neoplasia: 4-year end-of-study analysis of the randomised, double-blind PATRICIA trial. Lancet Oncology;13(1):89–99. Copyright 2012, with permission from Elsevier.