PT - JOURNAL ARTICLE AU - Rizzo, Toni ED - Pivot, Xavier TI - Adjuvant Trastuzumab for 6 versus 12 Months in Patients with Early Breast Cancer DP - 2012 01 TA - MD Conference Express PG - 12--13 VI - 12 IP - 15 4099 - http://mdc.sagepub.com/content/12/15/12.short 4100 - http://mdc.sagepub.com/content/12/15/12.full AB - The Finland Herceptin [FinHer] trial results and concerns about cardiac toxicity with trastuzumab provided the rationale for the Trastuzumab for 6 Months or 1 Year in Treating Women with Nonmetastatic Breast Cancer That Can Be Removed by Surgery [PHARE; NCT00381901] trial. The primary objective of this noninferiority trial was to compare the effect of 6 versus 12 months of adjuvant treatment with trastuzumab on disease-free survival in patients with HER2-positive early breast cancer.