RT Journal Article
SR Electronic
A1 Vinall, Phil
T1 First Large-Scale Platelet Function Evaluation in an Acute Coronary Syndrome Trial: The Trilogy ACS-Platelet Function Substudy
JF MD Conference Express
YR 2012
FD SAGE Publications
VO 12
IS 18
SP 14
OP 15
DO 10.1177/155989771218008
UL http://mdc.sagepub.com/content/12/18/14.abstract
AB In a platelet function substudy of A Comparison of Prasugrel and Clopidogrel in Acute Coronary Syndrome Subjects [TRILOGY ACS; NCT00699998] trial, patients with an acute coronary syndrome treated with prasugrel experienced significantly lower platelet reactivity compared with patients treated with clopidogrel. However, there was no relationship between platelet reactivity and the occurrence of ischemic outcomes, nor were there significant differences in the rates of the composite endpoint of cardiovascular death, myocardial infarction and stroke, or TIMI major bleeding between the 2 treatment groups enrolled in the platelet function substudy.