Summary

Patients with sputum-positive tuberculosis had similar negative culture rates after 8 weeks of treatment with rifapentine or rifampin, according to results of the TBTC Study 29 [NCT00694629]. By solid media analysis, 91.4% of the rifapentine group and 89.1% of the rifampin group had negative cultures. By liquid media, the negative-culture rates were 74.6% with rifapentine and 70.1% with rifampin.