RT Journal Article SR Electronic A1 Buckley, Rita T1 ISAR-REACT 4 – Bivalirudin Similar to Abciximab/Heparin in Reducing Ischemic Outcomes in NSTEMI and Has Significantly Less Bleeding JF MD Conference Express YR 2011 FD SAGE Publications VO 11 IS 15 SP 14 OP 15 DO 10.1177/155989771115008 UL http://mdc.sagepub.com/content/11/15/14.abstract AB A strategy of intravenous abciximab (a glycoprotein [GP] IIb/IIIa inhibitor) plus unfractionated heparin, compared with bivalirudin, an IV direct thrombin inhibitor, failed to improve clinical outcomes and increased the risk of bleeding in patients with acute non-ST-segment elevation myocardial infarction (NSTEMI) who were undergoing percutaneous coronary intervention, according to results of the ISAR-REACT 4 trial [NCT00373451].