RT Journal Article SR Electronic A1 Sinclair, Heather Q. T1 The Safety and Tolerability of Betrixaban Therapy JF MD Conference Express YR 2010 FD SAGE Publications VO 10 IS 2 SP 14 OP 15 DO 10.1177/155989771002007 UL http://mdc.sagepub.com/content/10/2/14.2.abstract AB The oral direct factor Xa inhibitor betrixaban, at doses of 40 mg, 60 mg, and 80 mg once daily, is safe and well tolerated compared with dose-adjusted warfarin in patients with nonvalvular atrial fibrillation (AF) or atrial flutter. This article presents results from the Phase II, randomized, multicenter EXPLORE-Xa Trial [NCT00742859].