PT - JOURNAL ARTICLE AU - Sinclair, Heather Q. ED - Ezekowitz, Michael D. TI - The Safety and Tolerability of Betrixaban Therapy DP - 2010 May 01 TA - MD Conference Express PG - 14--15 VI - 10 IP - 2 4099 - http://mdc.sagepub.com/content/10/2/14.2.short 4100 - http://mdc.sagepub.com/content/10/2/14.2.full AB - The oral direct factor Xa inhibitor betrixaban, at doses of 40 mg, 60 mg, and 80 mg once daily, is safe and well tolerated compared with dose-adjusted warfarin in patients with nonvalvular atrial fibrillation (AF) or atrial flutter. This article presents results from the Phase II, randomized, multicenter EXPLORE-Xa Trial [NCT00742859].