RT Journal Article SR Electronic A1 Jacobson, Anne T1 CLOSURE I: No Reduction in Recurrent Stroke or TIA with Septal Closure JF MD Conference Express YR 2010 FD SAGE Publications VO 10 IS 10 SP 22 OP 23 DO 10.1177/155989771010015 UL http://mdc.sagepub.com/content/10/10/22.abstract AB Percutaneous closure of patent foramen ovale does not reduce the risk of recurrent stroke or transient ischemic attack of unknown origin compared with standard medical therapy alone, according to new findings from the CLOSURE I trial.