Irbesartan Fails to Prevent Most Vascular Events in Patients with AF

Summary

In the Atrial Fibrillation Clopidogrel Trial with Irbesartan for Prevention of Vascular Events [ACTIVE-I; NCT00249795], treatment with irbesartan failed to lower the risk of stroke, myocardial infarction, and vascular death compared with placebo in patients with atrial fibrillation (AF). However, irbesartan may have a role in preventing heart failure, recurrent embolic events, and cardiovascular hospitalizations in patients with AF.

  • Cerebrovascular Disease
  • Hypertensive Disease
  • Arrhythmias Clinical Trials
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