PT - JOURNAL ARTICLE AU - Vinall, Phil ED - Davis, Stephen M. TI - Results of EPITHET DP - 2008 May 01 TA - MD Conference Express PG - 11--12 VI - 8 IP - 1 4099 - http://mdc.sagepub.com/content/8/1/11.short 4100 - http://mdc.sagepub.com/content/8/1/11.full AB - Intravenous recombinant tissue plasminogen activator (tPA) is recommended for the treatment of acute ischemic stroke within the first 3 hours of stroke onset. The objective of the Echoplanar Imaging Thrombolytic Evaluation Trial [EPITHET] was to evaluate the effect of the administration of tPA 3–6 hours after stroke onset as measured by echoplanar magnetic resonance imaging (MRI), diffusion-weighted MRI, and perfusion-weighted MRI.