Bivalirudin Not Superior to Unfractionated Heparin in Patients Receiving 600 mg Clopidogrel Prior to PCI

Summary

Bivalirudin failed to show a superior “net clinical benefit” compared with unfractionated heparin (UFH) in patients undergoing percutaneous coronary intervention in the Intracoronary Stenting and Antithrombotic Regimen-Rapid Early Action for Coronary Treatment 3 [ISAR-REACT 3] trial. However, bivalirudin reduced the rate of major and minor bleeding events in this patient population.

  • interventional techniques & devices clinical trials
  • thrombotic disorders
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