PT - JOURNAL ARTICLE AU - Sylvester, Bruce ED - Wijns, William TI - Darapladib May Slow Expansion of Atherosclerotic Plaques DP - 2008 Nov 01 TA - MD Conference Express PG - 21--22 VI - 8 IP - 6 4099 - http://mdc.sagepub.com/content/8/6/21.short 4100 - http://mdc.sagepub.com/content/8/6/21.full AB - Darapladib, a novel inhibitor of lipoprotein-associated phospholipase A2 (Lp-PLA2), may slow expansion of the necrotic core of atherosclerotic plaques in patients with acute coronary syndrome or other symptomatic coronary diseases, according to mixed results from the Integrated Biomarker and Imaging Study-2 [IBIS-2; NCT00268996].