RT Journal Article SR Electronic A1 Cunningham, Muriel T1 VALIDD: Lowering Blood Pressure Improves Diastolic Dysfunction JF MD Conference Express YR 2007 FD SAGE Publications VO 7 IS 1 SP 16 OP 17 DO 10.1177/155989770700700108 UL http://mdc.sagepub.com/content/7/1/16.2.abstract AB In a first randomized study of its kind, diastolic function, as assessed by noninvasive Doppler technology, was shown to be improved by lowering blood-pressure. The Valsartan in Diastolic Dysfunction [VALIDD] trial evaluated 482 patients from 41 North American sites with stage 1 or 2 essential hypertension using the relatively new method of Doppler tissue imaging to determine myocardial relaxation velocities.