PT - JOURNAL ARTICLE AU - Cunningham, Muriel ED - Schatzberg, Alan F. TI - Agomelatine Demonstrates Broad Efficacy in Depression DP - 2007 Aug 01 TA - MD Conference Express PG - 15--16 VI - 7 IP - 2 4099 - http://mdc.sagepub.com/content/7/2/15.short 4100 - http://mdc.sagepub.com/content/7/2/15.full AB - Agomelatine, a melatonergic agonist and a selective 5-HT2c antagonist, is a novel antidepressant in development for major depressive disorder. This article discusses a meta-analysis of pooled data from three clinical studies. The objective of the meta-analysis was to determine whether gender or baseline severity of depression had any influence on agomelatine efficacy.