PT - JOURNAL ARTICLE AU - Hoyle, Brian ED - Gallant, Joel E. TI - COBI Can Substitute for RTV in an HIV-1 Drug Regimen DP - 2014 Dec 01 TA - MD Conference Express PG - 18--19 VI - 14 IP - 28 4099 - http://mdc.sagepub.com/content/14/28/18.short 4100 - http://mdc.sagepub.com/content/14/28/18.full AB - Week 144 secondary end point results from a randomized, double-blind, double-dummy, active-controlled study involving 700 treatment-naïve HIV-1-infected patients have reaffirmed that cobicistat can be substituted for ritonavir in a drug regimen that seeks to boost the pharmacologic effect of atazanavir in combination with emtricitabine-tenofovir disoproxil fumarate.