A2NTX an Effective Substitute for OnabotulinumtoxinA in Poststroke Spasticity

Summary

An A2 subtype form of botulinum toxin, A2NTX, is an effective substitute for onabotulinumtoxinA and demonstrates significantly larger decreases in Modified Ashworth Scale ankle plantar extensor at 30 days after injection. Functional independence also significantly improves at 60 days, and there is less toxin spread into other areas of the body following A2NTX injection.

  • post-stroke
  • lower-limb spasticity
  • botulinum toxin
  • subtype 1 and 2
  • A2NTX
  • onabotulinumtoxinA
  • Modified Ashworth Scale
  • NCT01910363
  • neurology clinical trials
  • ischemia
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