Optimal Dosing and Titration of U-500R Improve Glycemic Control

Summary

Human regular U-500 insulin (U-500R) is more concentrated and has a higher potency level than U-100 insulin. Dosing errors can occur in patients on concentrated insulin. This study investigates dosing and titration of U-500R insulin using a twice- or thrice-daily dosing schedule.

  • U-100
  • U-500R
  • glycemic control
  • total daily dose
  • insulin
  • HbA1c
  • insulin resistance
  • endocrinology, diabetes & metabolism clinical trials
  • diabetes mellitus
  • hyperglycemia/hypoglycemia
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