Summary
Florian Holsboer, director of the Max-Planck Institute for Psychiatry for 25 years, called for a reengineering of the drug development process for antidepressants, meaning a shift from a focus on blockbuster drugs capable of treating all depression to use of biomarkers to target subsets of patients based on disease etiology.
- antidepressant
- depression
- monoaminergic
- imipramine
- CRH
- vasopressin
- ACTH
- hypothalamus
- pituitary
- HPA axis
- CRH receptor antagonist
- psychiatry & psychology clinical trials
- mood disorders
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