<?xml version='1.0' encoding='UTF-8'?><xml><records><record><source-app name="HighWire" version="7.x">Drupal-HighWire</source-app><ref-type name="Journal Article">17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Hoyle, Brian</style></author></authors><secondary-authors><author><style face="normal" font="default" size="100%">Sessler, Daniel I.</style></author></secondary-authors></contributors><titles><title><style face="normal" font="default" size="100%">Perioperative Clonidine Does Not Reduce CV Events in Patients Having Noncardiac Surgery (POISE-2)</style></title><secondary-title><style face="normal" font="default" size="100%">MD Conference Express</style></secondary-title></titles><dates><year><style  face="normal" font="default" size="100%">2014</style></year><pub-dates><date><style  face="normal" font="default" size="100%">2014-05-01 00:00:00</style></date></pub-dates></dates><pages><style  face="normal" font="default" size="100%">22-23</style></pages><abstract><style  face="normal" font="default" size="100%">Clonidine, a centrally acting a-agonist, does not reduce the risk of perioperative myocardial infarction or death in noncardiac surgery; however, it did cause clinically significant bradycardia and hypotension. The findings of the Perioperative Ischemic Evaluation-2 Trial [POISE-2; Devereaux PJ et al. N Engl J Med 2014] are discussed in this article.</style></abstract><number><style face="normal" font="default" size="100%">4</style></number><volume><style face="normal" font="default" size="100%">14</style></volume></record></records></xml>