LDL-C=low-density lipoprotein cholesterol.Reproduced from Stroes E et al. Anti-PCSK9 Antibody Effectively Lowers Cholesterol in Patients with Statin Intolerance: The GAUSS-2 Randomized, Placebo-controlled Phase 3 Clinical Trial of Evolocumab. J Am Coll Cardiol 2014 doi: 10.1016/j.jacc.2014.03.019. With permission from Elsevier.