RT Journal Article
SR Electronic
A1 Powers, Jenny
T1 Experts Discuss the Promises and Challenges with Targeted Therapies
JF MD Conference Express
YR 2014
FD SAGE Publications
VO 14
IS 3
SP 22
OP 23
DO 10.1177/155989771403014
UL http://mdc.sagepub.com/content/14/3/22.abstract
AB This article discusses targeted therapies in non—small cell lung cancer (NSCLC), including the rise and partial fall in efficacy seen with tyrosine kinase inhibitors (TKIs) of the anaplastic lymphoma kinase (ALK) pathway. Other topics include a review of strategies to target the epidermal growth factor receptor (EGFR), as well as the challenge of targeting new pathways.