Article Figures & Data
Figures
- Figure 1.
Brain Pathology of Alzheimer's Disease
Aβ=amyloid-β; ACT=antichymotrypsin; ApoE=apolipoprotein E; α2M=α-2 macroglobulin; IL-1=interleukin-1; TNFα=tumor necrosis factor-α.
Reproduced from Holtzman DM et al. Alzheimer's disease: the challenge of the second century. Sci Transl Med. 2011;3(77):77sr1. With permission from the American Association for the Advancement of Science.
- Figure 2.
AD Biomarker Changes Relative to Cognitive and Clinical Changes
Aβ=amyloid-β; AD=Alzheimer's disease; APOE=apolipoprotein E; CDR=clinical dementia rating; Max=maximum; Min=minimum; Mod.=moderate; Sev.=severe; SNP=single-nucleotide polymorphism.
Reproduced from Holtzman DM et al. Alzheimer's disease: the challenge of the second century. Sci Transl Med. 2011;3(77):77sr1. With permission from the American Association for the Advancement of Science.
- Figure 3.
Effect of Amyloid-β Immunization on Learning Ability of APP-Transgenic Mice
APP=amyloid precursor protein.
Reproduced from Janus C et al. A beta peptide immunization reduces behavioural impairment and plaques in a model of Alzheimer's disease. Nature. 2000;408(6815):979–982. With permission from the Nature Publishing Group.
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A Review of the Current Understanding and Treatment of Alzheimer's Disease
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