PT - JOURNAL ARTICLE AU - Vinall, Maria ED - Hartung, Hans-Peter TI - Evolving MS Treatment Strategies DP - 2014 Jul 01 TA - MD Conference Express PG - 26--29 VI - 14 IP - 29 4099 - http://mdc.sagepub.com/content/14/29/26.short 4100 - http://mdc.sagepub.com/content/14/29/26.full AB - The assessment of disease activity and burden has evolved from one based on clinical activity to one based on radiologic criteria (eg, number of new/enlarging T2 lesions, number of gadolinium-enhancing [Gd+] lesions, and brain atrophy/black holes). Treatment has moved from slowing disease progression to treatments (eg, natalizumab, fingolimod, interferon beta-1b [IFN-β-1b]) that improve and sustain function.