<?xml version='1.0' encoding='UTF-8'?><xml><records><record><source-app name="HighWire" version="7.x">Drupal-HighWire</source-app><ref-type name="Journal Article">17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Rizzo, Toni</style></author></authors><secondary-authors><author><style face="normal" font="default" size="100%">Arnold, Douglas L.</style></author></secondary-authors></contributors><titles><title><style face="normal" font="default" size="100%">ADVANCE Trial: PEG-IFN-β-1a Every 2 Weeks Significantly Improved Outcomes over 2 Years in RRMS</style></title><secondary-title><style face="normal" font="default" size="100%">MD Conference Express</style></secondary-title></titles><dates><year><style  face="normal" font="default" size="100%">2014</style></year><pub-dates><date><style  face="normal" font="default" size="100%">2014-06-01 00:00:00</style></date></pub-dates></dates><pages><style  face="normal" font="default" size="100%">8-8</style></pages><abstract><style  face="normal" font="default" size="100%">The 1-year results of the Efficacy and Safety Study of Peginterferon Beta-1a in Participants With Relapsing Multiple Sclerosis [ADVANCE; Calabresi PA et al. Lancet Neurol. 2014] demonstrated superior clinical and magnetic resonance imaging (MRI) outcomes as compared with placebo in patients with relapsing-remitting multiple sclerosis (RRMS). Post hoc analyses showed that significantly more patients treated with peginterferon beta-1a (PEG-IFN-β-1a) versus placebo had no evidence of disease activity (NEDA) at year 1 [Calabresi PA et al. ACTRIMS/ECTRIMS. 2013 (poster P514)]. The aim of this analysis of the ADVANCE trial was to evaluate MRI outcomes and NEDA over 2 years.</style></abstract><number><style face="normal" font="default" size="100%">29</style></number><volume><style face="normal" font="default" size="100%">14</style></volume></record></records></xml>