Reproduced from Wall NR, De La Parra M, Callaway EM, Kreitzer AC. Differential innervation of direct- and indirect-pathway striatal projection neurons. Neuron 2013;79:347–360. With permission from Elsevier.
P=parkin; PINK1=PTEN-induced putative kinase 1; Ub=ubiquitin.Reproduced from Koyano F, Okatsu K, Kosako H, et al. Ubiquitin is phosphorylated by PINK1 to activate parkin. Nature 2014;510:162–166. With permission from the Nature Publishing Group.