<?xml version='1.0' encoding='UTF-8'?><xml><records><record><source-app name="HighWire" version="7.x">Drupal-HighWire</source-app><ref-type name="Journal Article">17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Lederman, Lynne</style></author></authors><secondary-authors><author><style face="normal" font="default" size="100%">Volkmann, Elizabeth</style></author></secondary-authors></contributors><titles><title><style face="normal" font="default" size="100%">Forced Vital Capacity is Inadequate for Assessing ILD in SSc</style></title><secondary-title><style face="normal" font="default" size="100%">MD Conference Express</style></secondary-title></titles><dates><year><style  face="normal" font="default" size="100%">2014</style></year><pub-dates><date><style  face="normal" font="default" size="100%">2014-07-01 00:00:00</style></date></pub-dates></dates><pages><style  face="normal" font="default" size="100%">21-22</style></pages><abstract><style  face="normal" font="default" size="100%">Interstitial lung disease (ILD) in patients with systemic sclerosis (SSc) frequently results in ventilatory restriction, a major cause of death in these individuals. Clinical trials in patients with SSc-related ILD have traditionally used forced vital capacity percentage (FVC%) predicted as a primary outcome measure [Hoyles RK et al. Arthritis Rheum 2006; Tashkin DP et al. N Engl J Med 2006]. This article discusses the development of a composite outcome measure to assess treatment response in patients with SSc—ILD in clinical studies, and to create a more comprehensive measure than FVC% alone.</style></abstract><number><style face="normal" font="default" size="100%">17</style></number><volume><style face="normal" font="default" size="100%">14</style></volume></record></records></xml>