RT Journal Article
SR Electronic
A1 Nichols, Emma Hitt
T1 Acetaminophen Improves Kidney Function in Severe Sepsis
JF MD Conference Express
YR 2014
FD SAGE Publications
VO 14
IS 11
SP 20
OP 21
DO 10.1177/155989771411013
UL http://mdc.sagepub.com/content/14/11/20.abstract
AB Administration of acetaminophen to patients with severe sepsis and detectable plasma levels of cell-free hemoglobin (CFH) improved kidney function but did not appear to reduce oxidative injury. This article presents data from the Phase 2a randomized controlled trial of Acetaminophen for the Reduction of Oxidative Stress in Severe Sepsis trial [ACROSS; NCT01739361; Janz DR et al. Am J Respir Care Med 2014.]