Summary

AMG 157 is a human antithymic stromal lymphopoietin (TSLP) monoclonal immunoglobulin-2? molecule that blocks the interaction between TSLP and its receptor, a process that is thought to be important in initiating allergic inflammation. This article presents data from the Double-Blind, Multiple Dose Study in Subjects With Mild Atopic Asthma study [NCT01405963; Gauvreau GM et al. Am J Crit Care Med 2014].