Distribution of Changes in Systolic Blood Pressure
GFR=glomerular filtration rate; RAAS=renin-angiotensin-aldosterone system; SNS=sympathetic nervous system.Reproduced with permission from Elsevier from Krum H, Schlaich MP, Sobotka PA, et al. Percutaneous renal denervation in patients with treatment-resistant hypertension: final 3-year report of the Symplicity HTN-1 study. Lancet 2014;383(9917):622–629.