Summary

Empagliflozin is a potent and selective inhibitor of sodium glucose cotransporter 2. This article discusses an extension study, the Safety and Efficacy of Empagliflozin (BI 10773) and Sitagliptin Versus Placebo Over 76 Weeks in Patients With Type 2 Diabetes study [EMPA-REG EXTEND MET; NCT01289990], assessed the long-term safety, tolerability, and efficacy of the empagliflozin add-on regimen.